BIBLIOGRAPHY
Byrns, M, Steckelbroeck, S and Penning, TM. 2008. An indomethacin
analogue, N-(4-chlorobenzoyl)- melatonin, is a selective inhibitor of aldo-keto
reductase 1C3 (type 2 3a-HSD, type 5 17b--HSD, and
prostaglandin F synthase), a potential target for the treatment of hormone
dependent and hormone independent malignancies. Biochem Pharmacol
75: 484-93. PMCID: PMC2245880
Penning, TM, Lee, S-H, Jin, Y, Gutierrez, A and Blair, IA. 2010. Liquid chromatography-mass spectrometry (LC-MS) of steroid hormone metabolites and its applications. J Steroid Biochem Mol Biol 121: 546-55, 2010. PMCID: PMC 2894289. Adeniji, AO, Twenter, BM, Byrns, MC, Jin, Y, Winkler, JD, and Penning, TM. 2011. Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3 ). Bioorg Med Chem Lett 21: 1464-8. PMCID:PMC3057412 Adeniji, AO, Twenter, BM, Byrns, MC, Jin, Y, Chen, M, Winkler, JD, and Penning, TM. 2012. Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships. J Med Chem 55: 2311-23. PMCID PMC3298089 Chen, M, Adeniji, AO, Twenter, BM, Winkler, JD, Christianson, DW, and Penning TM. 2012. Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Bioorg Med Chem Lett 22: 3492-7. PMCID:PMC3348334 Liedtke AJ, Adeniji AO, Chen M, Byrns MC, Jin Y, Christianson DW, Marnett LJ, Penning TM. 2013. Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer. J Med Chem 56: 2429-46. PMCID: PMC3638264 Tamae, D, Byrns, M, Marck, B, Mostaghel, EA, Nelson, PS, Lange, P, Lin, D, Taplin, M-E, Balk, S, Ellis, W, True, L, Vessella, R, Montgomery, B, Blair, IA, and Penning, TM. 2013. Development, validation and application of a stable Isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/ mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum. J Steroid Biochem Mol Biol 138C: 281-289. PMCID In Progress NIHMS ID#491322 |